(Black Press Media file photo)

Vaccine against fentanyl shows promising results in rats: U.S. study

Rats chose food more times instead of fentanyl after receiving the vaccine treatment

A vaccine against fentanyl addiction is showing promising results in a recent study.

Research published in the American journal Neuropsychopharmacology last week found that a fentanyl antigen (an antigen triggers the production of antibodies) combined with a type of tetanus vaccine decreased drug-taking behaviour in rats and increased food choices, according to a news release.

British Columbia reported more than 1,300 illicit drug overdose deaths related to fentanyl in 2018, an increase of seven per cent from 2017.

“More effective and readily available treatments for opioid use disorder are needed to tackle the current crisis,” said lead authors Kim Janda, a professor at Scripps Research in San Diego, and Dr. Matthew Banks of the Virginia Commonwealth University School of Medicine.

READ MORE: Health Canada tightens marketing requirements for opioid prescriptions

“One strategy includes using opioid-targeted vaccines to elicit antibody production by the host’s immune system that recognize and block the passage of a specific opioid into the brain and peripheral organs/tissue.”

The study focused on the rats’ behavioural patterns and the number of times they chose fentanyl injections or food.

Before the treatment, rats chose a large amount of fentanyl, but within four weeks of being vaccinated, the number of times they chose the drug decreased.

The effectiveness of the vaccine has not been studied in humans.



joti.grewal@bpdigital.ca

Like us on Facebook and follow us on Twitter

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Citing stability, B.C. Premier calls snap election for Oct. 24

John Horgan meets with Lieutenant Governor to request vote

Routine medical check for adult canadians; what you need to know

Preventive Medicine is a proactive method of health care delivery. Its’ aim… Continue reading

Grant to provide solar panel to coho hatchery

And work on expansion is proceeding

Council shifts focus on highway utility line project

Council has decided not to seek a meeting with the chair of… Continue reading

B.C. reports 96 new COVID-19 cases, one hospital outbreak

61 people in hospital as summer ends with election

‘Unprecedented’ coalition demands end to B.C. salmon farms

First Nations, commercial fishermen among group calling for action on Cohen recommendations

Earthquake off coast of Washington recorded at 4.1 magnitude

The quake was recorded at a depth of 10 kilometres

B.C.’s top doctor says she’s received abuse, death threats during COVID-19 response

Henry has become a national figure during her time leading B.C.’s response to the COVID-19 pandemic

BC Liberals must change gears from election cynicism, focus on the issues: UBC professors

COVID-19 response and recovery is likely to dominate platforms

Join Black Press Media and Do Some Good

Pay it Forward program supports local businesses in their community giving

B.C. could be without a new leader for multiple weeks after Election Day: officials

More than 20K mail-in voting packages were requested within a day of B.C. election being called

Vancouver Island sailor stranded in U.S. hospital after suffering massive stroke at sea

Oak Bay man was attempting to circumnavigate the world solo

Majority needed to pass COVID-19 budget, B.C. premier says

John Horgan pushes urgent care centres in first campaign stop

Most Read